Scientific research is essential to grow our knowledge of the role of different nutrients, bioactive chemicals, or other ingredients in nutrition and health. Conducting scientific studies is not just important for growing our knowledge, but also for substantiating claims on foods, beverages, or supplements. This substantiation ensures that a product is truly delivering the intended health benefit (e.g. “supports joint health”).
There are many types of scientific studies and each have an important role to play. Although some types of research would be considered the stronger than others to support a role of an ingredient in health, science is a journey and all types of evidence are important. We often start with study designs like those at the top of the table to build a basic understanding, such as animal or cell studies, then the knowledge journey is continued through the various types of human studies.
One important thing to note when evaluating studies on nutrition ingredients is that many studies are done on products that are a specific strain, such as probiotics, or undergo specific processing or extraction methods, such as water vs oil extraction. In the latter case, water extraction may extract different bioactive components than oil extraction. In the case of probiotics, different strains have very diverse genetic makeups and biochemistry. This means that results from one study cannot always be extrapolated or generalized. For example, one cannot assume a beta glucan isolated from mushroom has the same effect on immune health that may have been shown by a beta glucan isolated from yeast in a clinical trial.
Our areas of research expertise include immune health ingredients, probiotics, proteins, fibres, healthy fats, and botanical extracts. Learn more about the studies conducted on Kerry ingredients by our scientific network on this page, as well as supporting research.
Bioactive ingredients – Yeast Beta Glucans
Beta glucans are fibers found in a variety of foods including oats, barley, seaweed, as well as many types microorganisms (bacteria, yeast and fungi). While they all share a “common” ß form of chemical bond between the individual glucose units, there are many subtle, but important differences in structure within the beta glucan family that lead to large differences in function and potential health benefits. See health benefits of each beta glucan source here – Immunity Ingredients At-A-Glance: Beta Glucans. When choosing a beta glucan, it is key to focus on what clinical research is available to support the ingredient’s mechanism of action, demonstrate effectiveness for the desired benefit, and show the safety of that specific strain or ingredient.
Wellmune® (yeast beta glucan) – Immune health
Yeast-derived beta glucans usually originate from either baker’s yeast or brewer’s yeast. Even though both are beta 1,3/1,6 glucan from Saccharomyces cerevisiae, the source matters—the beta glucans extracted from the cell walls of baker’s yeast have a different molecular branching and linkage pattern from that of brewer’s yeast, which influences the immune-modulating properties of the final product. Research supports the immune-modulating properties of baker’s yeast beta glucan—but different strains produce beta 1,3/1,6 glucans with different molecular patterns that affect their immunomodulatory activity.
Yeast Beta Glucan Research Studies
Boutros JA, Magee AS, Cox D. ‘Comparison of structural differences between yeast β-glucan sourced from different strains of saccharomyces cerevisiae and processed using proprietary manufacturing processes’. Food Chemistry. 2021 Jul 28; 367:130708.
De Marco Castro E, Calder PC, Roche HM. (2020) b-1,3/1,6 glucans and Immunity: State of the Art and Future Directions. Molecular Nutrition and Food Research, https://doi.org/10.1002/mnfr.201901071.
Eunice Mah, Valerie N. Kaden, Kathleen M. Kelley & DeAnn J. Liska (2018): Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. Journal of Dietary Supplements, DOI:10.1080/19390211.2018.1495676.
McFarlin BK, Venable AS, Carpenter KC, Henning AL, Ogenstad S. (2017) Oral Supplementation with Baker’s Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise. Frontiers in Physiology 8:786.
Fuller R, Moore MV, Lewith G, Stuart BL, Ormiston RV, Fisk HL, Noakes PS, Calder PC. (2017) Yeast-Derived Beta 1,3/1,6 Glucan, Upper Respiratory Tract Infection and Innate Immunity in Older Adults. Nutrition 39-40:30-35.
Meng F. (2016) Baker’s Yeast Beta-Glucan Decreases Episodes of Common Childhood Illness In 1 to 4-Year-Old Children during Cold Season in China. Journal of Nutrition & Food Sciences 6:518.
Pontes MV, Ribeiro TCM, Ribeiro H, de Mattos AP, Almeida IR, Leal VM, Cabral GN, Stolz S, Zhuang W, Scalabrin DMF. (2016) Cow’s Milk-Based Beverage Consumption in 1- to 4-Year-Olds and Allergic Manifestations: an RCT. Nutrition Journal 15:19-28.
Li F, Jin X, Liu B, Zhuang W, Scalabrin D. (2014) Follow-up Formula Consumption in 3- to 4-Year-Olds and Respiratory Infections: An RCT. Pediatrics 133:e1533-40.
McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. (2013) Baker’s Yeast Beta Glucan Supplementation Increases Salivary IgA and Decreases Cold/Flu Symptomatic Days After Intense Exercise. Journal of Dietary Supplements 10:171-183.
Carpenter KC, Breslin WL, Davidson T, Adams A, McFarlin BK. (2013) Baker’s Yeast Beta-Glucan Supplementation Increases Monocytes and Cytokines Post-Exercise: Implications of Infection Risk? British Journal of Nutrition 109:478-486.
Talbott SM, Talbott JA, Talbott TL, Dingler E. (2013) ß-Glucan Supplementation, Allergy Symptoms and Quality of Life in Self-Described Ragweed Allergy Sufferers. Food Science & Nutrition 1:90-101.
Fuller R, Butt H, Noakes PS, Kenyon J, Yam TS, Calder PC. (2012) Influence of Yeast-Derived 1,3/1,6 Glucopolysaccharide on Circulating Cytokines and Chemokines with Respect to Upper Respiratory Tract Infections. Nutrition 28:665-669.
Talbott SM, Talbott JA. (2012) Baker’s Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women. Journal of the American College of Nutrition 31:295-300.
Talbott S, Talbott J. (2010) Beta 1,3/1,6 Glucan Decreases Upper Respiratory Tract Infection Symptoms and Improves Psychological Well-Being in Moderate to Highly-Stressed Subjects. Agro FOOD Industry Hi-Tech 21:21-24.
Talbott S, Talbott J. (2009) Effect of Beta 1,3/1,6 Glucan on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. Journal of Sports Science and Medicine 8:509-515.
Feldman S, Schwartz HI, Kalman DS, Mayers A, Kohrman HM, Clemens R, Krieger DR. (2009) Randomized Phase II Clinical Trials of Wellmune® for Immune Support During Cold and Flu Season. Journal of Applied Research 9:30-42.
Harger-Domitrovich SG, Domitrovich JW, Ruby BC. (2008) Effects of an Immunomodulating Supplement on Upper Respiratory Tract Infection Symptoms in Wildland Firefighters. Medicine & Science in Sports & Exercise 40:S353.
Probiotics are defined by the World Health Organisation as “Live microorganisms which when administered in adequate amounts confer a health benefit on the host.” While common vegetative probiotics strains are fragile through many processing conditions that foods or beverages typically go through (e.g., high heat or low moisture), spore-forming strains are resilient to heat and other harsh conditions due to their spore coat. They only germinate once conditions are ideal, such as in the human digestive tract, and as a result they can survive most manufacturing processes.
Every bacteria strain has its own strain-specific genomic and phenotypic characteristics.
- No two strains of bacteria are identical.
- Safety and clinical data from one strain cannot be used to support the safety and efficacy of another strain.
Visit The Human Microbiome: Beyond Digestive Health – KHNI (kerry.com) for more information on the human microbiome.
BC30™ (Bacillus coagulans GBI-30, 6086®) – Digestive health, immune health, protein absorption
BC30™ (Bacillus coagulans GBI-30, 6086®) is a spore-forming, patented probiotic. It’s a highly stable probiotic with the ability to survive harsh manufacturing processes, product shelf-life and the journey through the digestive system.
For this strain, research has supported a role in:
- Digestive Health
- Immune Health
- Protein Absorption
BC30™ (Bacillus coagulans GBI-30, 6086®) Research Studies
A Prospective, Randomized, Double-blind, Placebo-controlled Parallel-group Dual Site Trial to Evaluate the Effects of a Bacillus coagulans–based Product on Functional Intestinal Gas Symptoms. Kalman DS, Schwartz HI, Alvarez P, Feldman S, Pezzullo JC, Krieger DR. BMC gastroenterology 2009;9:85.
Bacillus coagulans Significantly Improved Abdominal Pain and Bloating in Patients With IBS. Hun L. Postgrad Med 2009;121:119-24.
Effects of A Proprietary Bacillus coagulans Preparation on Symptoms of Diarrhea–Predominant Irritable Bowel Syndrome. Dolin BJ. Methods Find Exp Clin Pharmacol 2009;31:655-9.
Bacillus coagulans GBI-30, 6086 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican scholar-aged children by modulating immune-related proteins. Anaya-Loyola MA, Enciso-Moreno JA, Lopez-Ramos JE, Garcia-Marin G, Orozco Alvarez MY, Vega-Garcai AM, Mosqueda J, Garcia-Gutierrez DG, Keller D, Perez-Ramirez IF. 2019. Food Research International.
A Controlled Clinical Trial to Evaluate the Effect of BC30 on Immunological Markers. Kimmel M, Keller D, Farmer S, Warrino DE. Find Exp Clin Pharmacol 2010;32:129-32.
Bacillus coagulans GBI-30, 6086 improves amino acid absorption from milk protein. Richard A. Stecker, Moon JM, Russo TJ, Ratliff KM, Mumford PW, Jäger R, Purpura M, & Kerksick CM. 2020. Nutrition & Metabolism.
Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery. Jäger R, Shields KA, Lowery RP, et al. 2016. PeerJ.
Bacillus Coagulans GBI-30, 6086 Improves Amino Acid Absorption from Plant Protein in Older Women. Gross KN, Walden KE, Hagele AM, et al. Probiotics & Antimicro. Prot. 2022. https://doi.org/10.1007/s12602-022-10028-4
Unlike spore-forming probiotics, vegetative probiotics do not have a spore coat and are found in foods or beverages in their living, active state. Examples include Lactobacillus and Bifidobacterium.
LC40® (Lactobacillus fermentum CECT5716) – Women’s health, infant health, immune health
LC40® is a probiotic derived from the human breast milk of healthy mothers.
For women: LC40® has been clinically shown to support women’s health by preventing premature cessation of breastfeeding due to pain and alleviating symptoms of mammary dysbiosis.
For babies: LC40® has been shown to reduce the risk of respiratory tract infections and diarrhea in babies.
LC40® (Lactobacillus fermentum CECT5716) Research Studies
Arroyo R, et al. Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk. Clin Infect Dis. 2010;50(12):1551-8.
Hurtado JA, et al. Lactobacillus fermentum CECT5716, a human milk probiotic strain, reduces the incidence and symptoms of mastitis in lactating women. Breastfeed Med. 2017;12(4):202-209.
Maldonado-Lobón JA, et al. Lactobacillus fermentum CECT5716 reduces Staphylococcus load in the breast milk of lactating mothers suffering breast pain: A randomized controlled trial. Breastfeed Med. 2015;10:425-32
Gil-Campos M, et al. Lactobacillus fermentum CECT 5716 is safe and well tolerated in infants of 1–6 months of age: A Randomized Controlled Trial. Pharmacol Res. 2012;65(2)231-8.
Maldonado J, et al. Evaluation of the safety, tolerance and efficacy of 1-year consumption of infant formula supplemented with Lactobacillus fermentum CECT5716 Lc40 or Bifidobacterium breve CECT7263: a randomized controlled trial. BMC Pediatr. 2019;19(1):361.
Maldonado J, et al. Human Milk Probiotic Lactobacillus fermentum CECT5716. Reduces the Incidence of Gastrointestinal and Upper Respiratory Tract Infections in Infants. J Pediatr Gastroenterol Nutr. 2012;54: 55–61.
Maldonado-Lobón JA, et al. Long-term safety of early consumption of Lactobacillus fermentum CECT5716: A 3-year follow-up of a randomized controlled trial. Pharmacol Res. 2015;95-96:12-9
BfM26TM (Bifidobacterium breve CECT7263) – Infant Health
BfM26TM is a clinically supported patented probiotic isolated from women’s breast milk that has been studied for its role in treating infantile colic.
BfM26(TM) (Bifidobacterium breve CECT7263) Research Studies
Maldonado et al. Efficacy of Bifidobacterium breve CECT7263 for infantile colic treatment. Beneficial Microbes, 2020; online
Maldonado J, et al. Evaluation of the safety, tolerance and efficacy of 1-year consumption of infant formula supplemented with Lactobacillus fermentum CECT5716 Lc40 or Bifidobacterium breve CECT7263: a randomized controlled trial. BMC Pediatr. 2019;19(1):361.
Bio-K+ (L. casei LBC80R + L. acidophilus CL1285 + L. rhamnosus CLR2) – Digestive health, Immune health
Bio-K+ is a unique three-strain probiotic formulation containing L. acidophilus CL1285, L. casei LBC80R, and L. rhamnosus CLR2 studied for its role in digestive health in individuals being treated with antibiotics or individuals with IBS.
Bio-K+ has been shown in multiple clinical trials and observational studies, conducted in hospital settings, to reduce the incidence of antibiotic-associated diarrheas (AAD) and Clostridioides (Clostridium) difficile-associated diarrheas (CDAD). Studies have also shown improvements in stool consistency and frequency, reduced abdominal pain, and improved quality of life in individuals with diarrhea-predominant irritable bowel syndrome (IBS).
Bio-K+ Research Studies
Gao, X.W., M. Mubasher, C. Zhang, C. Reifer, K. Zhang. Dose-response Efficacy of a Probiotic Formula in Reducing Antibiotic-associated Diarrhea and Clostridium difficile-associated Diarrhea Incidence: A Double-blind, Randomized, Placebo-Controlled Study, 2010. American Journal of Gastroenterology, 105(7):1636-1641.
Beausoleil, M., N. Fortier, S. Guénette, A. L’Écuyer, M. Savoie, M. Franco, J. Lachaîne, K. Weiss. Effect of a fermented milk combining Lactobacillus acidophilus CL1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: A randomized, double-blind, placebo-controlled trial, 2007. Canadian Journal of Gastroenterology, 21(11):732-736.
Maziade, P.J., N. Ship, J.C. Sniffen, E.J.C Goldstein. Enhanced Clostridioides difficile infection prevention with a pharmacy-controlled policy that adds a three-strain Lactobacillus probiotic concomitantly to antibiotic therapy, 2021. Clinical Infectious Diseases
Maziade, P.J., P. Pereira, E.J.C. Goldstein. A decade of experience in primary prevention of Clostridium difficile infection at a community hospital using the probiotic combination Lactobacillus acidophilus CL1285, L. casei LBC80R and L. rhamnosus CLR2 (Bio-K+), 2015. Clinical Infectious Diseases, 60 (Suppl 2):S144-S147.
Maziade, P.J., A. Andriessen, P. Pereira, B. Currie, E.J.C. Goldstein. Impact of adding prophylactic probiotics to a bundle of standard preventative measures for Clostridium difficile infections: enhanced and sustained decrease in the incidence and severity at a community hospital, 2013. Current Medical Research and Opinion, 29(10):1341-1347.
McFarland, L.V., N. Ship, J. Auclair, M. Millette. Primary prevention of Clostridium difficile infections with a specific probiotic combining Lactobacillus acidophilus, L. casei, and L. rhamnosus strains: assessing the evidence, 2018. Journal of Hospital Infection, 99(4):443-452
Preston, K., R. Krumian, J. Hattner, D. de Montigny, M. Stewart, S. Gaddam. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study, 2018. Beneficial Microbes, 9(5):697-706.
Botanical extracts are ingredients or compounds isolated directly from plants. In the case of health and nutrition, they are often extracts rich in polyphenols, vitamins, minerals, or other chemicals of interest thought to be linked to a certain health outcome. A commonly known botanical extract would be curcumin-rich turmeric extract.
Not all plant extracts are supported by science. In the case above, curcumin is thought to be the compound in turmeric responsible for specific health benefits. However, curcmin content can vary from plant to plant. Extracts should be standardized to specific levels of the bioactive components that are linked to health benefits if they are to be used for health and nutrition applications (food, beverage, supplements).
Caronositol Fertility® (Myo-inositol and D-Chiro inositol) – Women’s health
Caronositol Fertility® is a patented combination of Myo-inositol (extracted from corn phytin) and D-Chiro inositol (extracted from the fruit of the carob bean tree) studied for a role in fertility in women with fertility challenges related to Polycystic Ovary Syndrome (PCOS)
Caronositol Fertility® Research Studies
Nicolas Mendoza, Maria Paz Diaz-Ropero, Miguel Aragon, Vicente Maldonado, Placido Llaneza, Juan Lorente, Raquel Mendoza-Tesarik, Jose Maldonado-Lobon, Monica Olivares & Juristo Fonolla (2019) Comparison of the effect of two combinations of myo-inositol and D-chiroinositol in women with polycystic ovary syndrome undergoing ICSI: a randomized controlled trial, Gynecological Endocrinology, 35:8, 695-700, DOI: 10.1080/09513590.2019.1576620
(2020) High dose of d-chiro-inositol improves oocyte quality in women with polycystic ovary syndrome undergoing ICSI: a randomized controlled trial, Gynecological Endocrinology, 36:5, 398-401, DOI: 10.1080/09513590.2019.1681959
Sensoril® (Ashwagandha root & leaf extract) – Cognitive health
Ashwagandha (Withania somnifera) is an herb commonly used in ayuverdic medicine. Sensoril Ashwagandha is derived from a unique blend of both leaves and roots of the Withania somnifera plant by a totally aqueous extraction process. Clinical studies have explored its role in reducing stress, improving sleep quality, improving mood, and enhancing focus.
Sensoril® (Ashwagandha root & leaf extract) Research Studies
A standardized Withania somnifera extract reduces stress-related parameters in chronically stressed humans: A double-blind, randomized, placebo-controlled study. B Auddy et al. Journal of the American Nutraceutical Association (JANA), 2008; 11(1): 51 – 57.
Effects of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants. U Pingali et al. Phamacognosy Research, 2014; 6(1): 12 – 18.
Randomized placebo-controlled adjunctive study of an extract of Withania somnifera for cognitive dysfunction in bipolar disorder. KN Roy Chrngappa et al. Journal of Clinical Psychiatry, 2013; (74)11: 1076 – 1083.
Effect of Withania somnifera extract on mental stress induced changes in hemodynamic properties and arterial wave reflections in healthy subjects. U Pingali et al. Current Topics in Nutraceutical Research, 2013; 11(4): 151 – 158.
Evaluation of a highly standardized Withania somnifera extract on endothelial function and biomarkers of oxidative stress in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled study. U Pingali et al. International Journal of Ayurveda & Pharma Research, 2014; 2(3): 22 – 32.
A comparative study to evaluate the effect of highly standardized aqueous extracts of Phyllanthus emblica, Withania somnifera and their combination on endothelial dysfunction and biomarkers in patients with type 2 diabetes mellitus. U Pingali et al. International Journal of Pharmaceutical Sciences & Research (IJPPSR), 2014; 5(7): 2687 – 2697.
Evaluation of effect of highly standardized aqueous extract of roots and leaves of Withania somnifera on cold pressor test induced cardiovascular changes in healthy human subjects. R Pilli et al. International Journal of Basic & Clinical Pharmacology, 2016; 5(3): 873 – 878.
A randomized, double-blind, plaecbo-controlled study of efficacy and tolerability of Withania somnifera extracts in knee joint pain. GSH Ramakanth et al. Journal of Ayurveda and Integrative Medicine, 2016; 7(3): 151 – 157.
Ajunctive use of a standardized extract of Withania somnifera (ashwagandha) to treat symptom exacerbation in schizphrenia: A randomized, double-blind, placebo-controlled study. KN Roy Chengappa et al. Journal of Clinical Psychiatry, 2018; 79(5).
Effects of an aqueous extract of Withania somnifera on strength training adaptations and recovery: The STAR trial. TN Ziegenfuss et al. Nutrients, 2018; 10, 1807.
Evaluation of analgesic activity of standardized aqueous extract of Withania somnifera in healthy human volunteers using mechanical pain model. MNK Murthy et al. Journal of Clinical & Diagnostic Research, 2019; 13(1): FC01 – FC04.
A prospective, randomized, double-blind, placebo-controlled crossover study to evaluate the acute effect of a standardized aqueous extracct of Withania somnifera (ashwagandha) on transient insomnia. A Deshpande & N Irani. International Institute of Sleep Sciences. Not published (data analysis in progress).
AyuFlex® (Terminalia chebula extract) – Joint health
AyuFlex® is a standardized dried aqueous extract derived from the ancient Indian Ayurvedic fruits of Terminalia chebula. Obtained by a patented proprietary process and standardized to Chebulinic acid & Chebulagic acid (≥ 27.0%) and Low Molecular weight Hydrolyzable Tannins (≥ 39.0%). Clinical studies on AyuFlex have explored its role in joint mobility, comfort, and reduced pain.
AyuFlex® (Terminalia chebula extract) Research Studies
Evaluation of the analgesic activity of standardized aqueous extract of Terminalia chebula in healthy human participants using hot air pain model. CU Kumar et al. Journal of Clinical & Diagnostic Research, 2015; 9(5): FC01 – FC04.
A randomized, double-blind, placebo-controlled, cross-over study to evaluate analgesic activity of Terminalia chebula in healthy human volunteers using a mechanical pain model. VK Pokuri et al. Journal of Anaesthesiology Clinical Pharmacology, 2016; 32(3): 329 – 332.
A randomized, double-blind, placebo-controlled, parallel group clinical study to evaluate the analgesic effect of aqueous extract of terminalia chebula, a proprietary chromium complex, and their combination in subjects with joint discomfort. C Nutalapati et al. Asian Journal of Pharmaceutical & Clinical Research, 2016; 9(3): 264 – 269.
Effects of dietary supplementation with a standardized aqueous extract of Terminalia chebula fruit (AyuFlex®) on joint mobility, comfort, and functional capacity in healthy overweight subjects: A randomized placebo-controlled clinical trial. HL Lopez et al. BMC Complementary & Alternative Medicine, 2017; 17(1): 475.
Evaluation of Terminalia chebula extract for anti-arthritic efficacy and safety in osteoarthritic dogs. N Murdock et al. Journal of Veterinary Science & Technology, 2016; 7(1): 1000290.
Anti-osteoarthritic effects of Terminalia chebula fruit extract (AyuFlex®) in interleukin-1β-induced human chondrocytes and in rat models of monosodium iodoacetate (MIA)-induced osteoarthritis. HL Kim et al. Applied Sciences, 2020; 10(23): 8698.
Capros® (Amla Fruit) – Heart Health
Capros® is a natural botanical extract, derived from edible fruits of Amla (Phyllanthus emblica). Amla or Amalaki is the most used Ayurvedic ingredient in India. It is recognized as super antioxidant (ORACFN of 47,000 µmoles TE/g). The studies below have explored the role of Capros® in multiple aspects of cardiovascular health such as endothelial function, healthy lipid profiles, and blood flow.
Capros® (Amla Fruit) Research Studies
Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled study. U Pingali et al. Diabetes, Metabolic Syndrome and Obesity: Targets & Therapy, 2013; 6: 1 – 10.00
Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. N Fatima et al. Phytomedicine, 2013.
Evaluation of Phyllanthus emblica extract on cold pressor induced cardiovascular changes in healthy human subjects. N Fatima et al. Pharmacognosy Research, 2013; 6(1): 29 – 35.
A comparative study to evaluate the effect of highly standardized aqueous extracts of Phyllanthus emblica, Withania somnifera and their combination on endothelial dysfunction and biomarkers in patients with type II diabetes mellitus. U Pingali et al. International Journal of Pharmaceutical Sciences & Research (IJPSR), 2014; 5(7): 2687 – 2697.
Supplementation of a standardized extract from Phyllanthus emblica improves cardiovascular risk factors and platelet aggregation in overweight/class-1 obese adults. S Khanna et al. Journal of Medicinal Food, 2015; 18(4): 415 – 420.
Evaluation of the effect of a standardized aqueous extract of the fruits of Emblica officinalis on mental stress induced cardiovsacular changes in healthy human subjects. U Pingali et al. International Journal of Pharmaceutical Sciences & Research (IJPSR), 2017; 8(10): 4138 – 4146.
Evaluation of the effects of a standardized aqueous extract of Phyllanthus embilica fruits on endothelial dysfunction, oxidative stress, systemic inflammation and lipid profiles in subjects with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical study. U Pingali et al. BMC Complementary & Alternative Medicine, 2019; 19:97.
Omega-3 Fatty Acids
Omega-3 fatty acids serve many important roles in human health such as eye health, heart health, and brain health. You can read more about the function of Omega-3 fats in our white paper Benefits of Omega-3 Fatty Acids: What Does Science Say?
Eupoly-3® (Omega-3 from fish and algae) oils are naturally sourced omega-3 polyunsaturated fatty acids from fish or algae purified and blended to maximize stability and minimise off-flavour. The body of evidence for omega-3 fatty acids in health is broad, but you can see the studies done specifically on Eupoly-3® below.
Eupoly-3® (Omega-3 from fish and algae) Research Studies
Fonollá J, López-Huertas E, Machado FJ, Molina D, Álvarez I, Mármol E, Navas M, Palacín E, García-Valls MJ, Remón B, Boza JJ, Marti JL. 2009. Milk enriched with “healthy fatty acids” improves cardiovascular risk markers and nutritional status in human volunteers. Nutrition;25:408-414.
Carrero, EduardoLópez-Huertas, Luis M.Salmerón, Victoria E.Ramos, LuisBaró, Eduardo Ros. Simvastatin and supplementation with ω-3 polyunsaturated fatty acids and vitamins improves claudication distance in a randomized PILOT study in patients with peripheral vascular disease. Nutrition Research 2006; 26: 637-643.
Romeo J, Wärnberg J, García-Mármol E, Rodríguez-Rodríguez M, Diaz LE, Gómez-Martínez S, Cueto B, López-Huertas E, Cepero M, Boza JJ, Fonollá J, Marcos A. 2011. Daily consumption of milk enriched with fish oil, oleic acid, minerals and vitamins reduces cell adhesion molecules in healthy children. Nutr Metab Cardiovasc Dis;21:113-120.
Juristo Fonollá-Joya, Rebeca Reyes-García, Antonia García-Martín, Eduardo López-Huertas, Manuel Muñoz-Torres. Daily intake of milk enriched with n-3 fatty acids, oleic acid, and calcium improves metabolic and bone biomarkers in postmenopausal women. J Am Coll Nutr;35(6):529-536.
Carrero JJ, Fonollá J, Marti JL, Jiménez J, Boza JJ, López-Huertas E. 2007. Intake of fish oil, oleic acid, folic acid, and vitamins B-6 and E for 1 year decreases plasma C-reactive protein and reduces coronary heart disease risk factors in male patients in a cardiac rehabilitation program. J Nutr;137:384-390.
Dafina Petrova, María Asunción Bernabeu Litrán, Eduardo García-Mármol, María Rodríguez-Rodríguez, Belén Cueto Martín, Eduardo López-Huertas, Andrés Catena, Juristo Fonollá. 2018. Effects of fortified milk on cognitive abilities in school-aged children: results from a randomized-controlled trial. Eur J Nutr; DOI: 10.1007/s00394-018-1734-x.
Martín-Bautista E, Muñoz-Torres M, Fonollá J, Quesada M, Poyatos A, López-Huertas E. 2010. Improvement of bone formation biomarkers after 1-year consumption with milk fortified with eicosapentaenoic acid, docosahexaenoic acid, oleic acid, and selected vitamins. Nutr Res;30:320-326.