Our Research

Our areas of research expertise include immune health ingredients, probiotics, proteins, fibres, healthy fats, and botanical extracts. Learn more about the studies conducted on Kerry ingredients by our scientific network on this page, as well as supporting research.

Wellmune (Yeast Beta Glucan) - Immunity

b-1,3/1,6 glucans and Immunity: State of the Art and Future Directions.

De Marco Castro E, Calder PC, Roche HM. (2020). Molecular Nutrition and Food Research, https://doi.org/10.1002/mnfr.201901071.

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial.

Eunice Mah, Valerie N. Kaden, Kathleen M. Kelley & DeAnn J. Liska. (2018). Journal of Dietary Supplements, DOI:10.1080/19390211.2018.1495676.

Oral Supplementation with Baker’s Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise.

McFarlin BK, Venable AS, Carpenter KC, Henning AL, Ogenstad S. (2017). Frontiers in Physiology 8:786.

Bakers yeast beta-glucan decreases episodes of common childhood illness in 1 to 4 year old children during cold season in China

Zhou X. American Society for Parenteral and Enteral Nutrition (ASPEN), Clinical Nutrition Week 2016

Yeast-Derived 1,3/1,6 Glucopolysaccharide to Prevent Upper Respiratory Tract Infection and Modulate Circulating Cytokines and Chemokines in Older Adults

Fuller RJ, Moore MV, Lewith GL, Stuart BL, Noakes PS, Calder PC. Published on 20 June 2014 by Wellmune in Clinical Research, Research

Formula with docosahexaenoic acid, prebiotics, and beta-glucan supports respiratory and skin health in children

Scalabrin D, Ribeiro T, Peixoto de Matto A, Zhuang W, Stolz S, Pontes M, Almeida I, Godoy C, Gatto S, Leal V, Cabral G, Ribeiro H. April 2014 The FASEB Journal vol. 28 no. 1 Supplement 382.6

Differential regulation of oxidative burst by distinct β-glucan-binding receptors and signaling pathways in human peripheral blood mononuclear cells

Bose N, Wurst LR, Chan ASH, Dudney CM, LeRoux ML, Danielson ME., Will PM, Nodland SE, Patchen ML, Dalle Lucca JJ, Lebeda FJ and Vasilakos JP. Glycobiology (2014) doi: 10.1093/glycob/cwu005

Baker’s Yeast Beta Glucan Supplementation Increases Salivary IgA and Decreases Cold/Flu Symptomatic Days After Intense Exercise

McFarlin BK, CarpenterKC, Davidson T, McFarlin MA. J Diet Suppl. 2013 Sep;10(3):171-83. doi: 10.3109/19390211.2013.820248. Epub 2013 Aug 9.

Baker’s Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women

Talbott SM, Talbott JA. Journal of the American College of Nutrition vol. 31 no. 4 295-300

β-Glucan supplementation, allergy symptoms, and quality of life in self-described ragweed allergy sufferers

Talbott SM, Talbott JA, Talbott TL, Dingler E. Food Science & Nutrition (2012). Published by Wiley Periodicals. Open Access.

Baker’s Yeast Beta Glucan Supplementation Reduces The Number Of Cold/Flu Symptomatic Days After Completing A Marathon

Navalta JA, CarpenterKC, Breslin WL, Davidson T, McFarlin BK. American College of Sports Medicine 59th Annual Meeting

Baker’s yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk?

Carpenter KC, Breslin WL, Davidson T, Adams A, McFarlin BK. British Journal of Nutrition, FirstView Article : pp 1-9 Copyright © The Authors 2012

Influence of yeast-derived 1,3/1,6 glucopolysaccharide on circulating cytokines and chemokines with respect to upper respiratory tract infections

Fuller R, Butt H, Noakes PS, Kenyon J, Yam TS, Calder PC. Nutrition. 2012 Jun;28(6):665-9. doi: 10.1016/j.nut.2011.11.012. Epub 2012 Mar 30.

The Effects of Yeast β-Glucan Supplementation on Monocyte and Cytokine Response to Exercise

Carpenter KC, Breslin WL, Davidson T, Halliday T, Adams A, McFarlin BK. Presented at the International Society of Exercise Immunology, University of Oxford

Baker’s Yeast Beta-Glucan Supplement Reduces Allergy Symptoms and Improves Quality of Life in Ragweed Sufferers

Talbott SM, Talbott JA, Talbott TL, Dingler E. Presented at Experimental Biology 2011, Washington, D.C.

Beta-Glucan Supplement Reduces URTIs & Improves Mood State in Stressed Women

Talbott S, Talbott J, Cox D. Presented to the American College of Nutrition

Beta-glucan Supplement Reduces Upper Respiratory Tract Infections and Improves Mood State in Healthy Stressed Subjects

Talbott S, Talbott J, Cox D. Presented at Experimental Biology 2010 in Anaheim, Calif.

Effect of Beta 1,3/1,6 Glucan on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes

Talbott S, Talbott J. Journal of Sports Science and Medicine (2009). 8:509-515.

Randomized Phase II Clinical Trials of Wellmune WGP® for Immune Support During Cold and Flu Season

Feldman S, Schwartz HI, Kalman DS, Mayers A, Kohrman HM, Clemens R, Krieger DR. The Journal of Applied Research (2009) 9:20-42.

Effects of an Immunomodulating Supplement on Upper Respiratory Tract Infection Symptoms in Wildland Firefighters

Harger-Domitrovich SG, Domitrovich JW, Ruby BC. Medicine & Science in Sports & Exercise. 40(5):S353.

Probiotics - BC30 (Bacillus coagulans GBI-30, 6086)

Bacillus coagulans GBI-30, 6086 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican scholar-aged children by modulating immune-related proteins.

Anaya-Loyola MA, Enciso-Moreno JA, Lopez-Ramos JE, Garcia-Marin G, Orozco Alvarez MY, Vega-Garcai AM, Mosqueda J, Garcia-Gutierrez DG, Keller D, Perez-Ramirez IF. 2019. Food Research International.

A Controlled Clinical Trial to Evaluate the Effect of BC30 on Immunological Markers.

Kimmel M, Keller D, Farmer S, Warrino DE. Find Exp Clin Pharmacol 2010;32:129-32.

Bacillus coagulans GBI-30, 6086 improves amino acid absorption from milk protein.

Richard A. Stecker, Moon JM, Russo TJ, Ratliff KM, Mumford PW, Jäger R, Purpura M, & Kerksick CM. 2020. Nutrition & Metabolism.

Probiotics - Bio-K+ (L. casei LBC80R + L. acidophilus CL1285 + L. rhamnosus CLR2)

Effect of a fermented milk combining Lactobacillus acidophilus CL1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: A randomized, double-blind, placebo-controlled trial.

Beausoleil, M., N. Fortier, S. Guénette, A. L’Écuyer, M. Savoie, M. Franco, J. Lachaîne, K. Weiss. 2007. Canadian Journal of Gastroenterology, 21(11):732-736.

Enhanced Clostridioides difficile infection prevention with a pharmacy-controlled policy that adds a three-strain Lactobacillus probiotic concomitantly to antibiotic therapy.

Maziade, P.J., N. Ship, J.C. Sniffen, E.J.C Goldstein. 2021. Clinical Infectious Diseases, ciab414, Epub ahead of print.

Probiotics - Hereditum

Efficacy of Bifidobacterium breve CECT7263 for infantile colic treatment: an open-label, parallel, randomised, controlled trial.

Maldonado-Lobón JA, Blanco-Rojo R, Maldonado J, Ali MA, Almazán MV, Suanes-Cabello A, Callejón E, Jaldo R, Benavídes MR, Negrillo AM, Sañudo A, Rodríguez C, Bañuelos O, Fonollá J, Olivares M. Benef Microbes. 2020 Dec 22:1-14

The human milk probiotic Lactobacillus fermentum CECT 5716 reduces the incidence of gastrointestinal and respiratory infections in infants.  A Randomised Controlled Trial comparing a prebiotic containing follow-on formula vs the same formula plus probiotic.

Maldonado J, Cañabate F , Sempere L, Vela F, Sánchez AR, Narbona E, López-Huertas E, Geerlings A, Valero AD, Olivares M,  Lara-Villoslada F. J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):55-61

Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk.

Arroyo R, Martín V, Maldonado A, Jiménez E, Fernández L, Rodríguez JM. Clin Infect Dis . 2010 Jun 15;50(12):1551-8

Effects of Lactobacillus coryniformis K8 CECT5711 on the immune response to influenza vaccination and the assessment of common respiratory symptoms in elderly subjects: a randomized controlled trial.

Fonollá J, Gracián C, Maldonado-Lobón JA, Romero C, Bédmar A, Carrillo JC, Martín-Castro C, Cabrera AL, García-Curiel JM, Rodríguez C, Sanbonmatsu S, Pérez-Ruiz M, Navarro JM, Olivares M. Eur J Nutr. 2019 Feb;58(1):83-90.

Omega-3 fatty acids

Milk enriched with “healthy fatty acids” improves cardiovascular risk markers and nutritional status in human volunteers.

Fonollá J, López-Huertas E, Machado FJ, Molina D, Alvarez I, Mármol E, Navas M, Palacín E, García-Valls MJ, Remón B, Boza J, Marti JL. Nutrition. 2009 Apr;25(4):408-14

Еffects of fortified milk on cognitive abilities in school-aged children: results from a randomized-controlled trial.

Petrova D, Bernabeu Litrán  MA, García-Mármol  E , Rodríguez-Rodríguez  M, Cueto-Martín  B , López-Huertas  E, Catena  A , Fonollá  J. Eur J Nutr. 2019 Aug;58(5):1863-1872.

Botanical extracts - Elderpro Elderberry and Reishi extracts (immunity)

Effects of a Combination of Elderberry and Reishi Extracts on the Duration and Severity of Respiratory Tract Infections in Elderly Subjects: A Randomized Controlled Trial.

Gracián-Alcaide C, Maldonado-Lobón JA, Ortiz-Tikkakoski E, Gómez-Vilchez A, Fonollá J,  López-Larramendi JL, Olivares M and Blanco-Rojo R. Appl. Sci. 2020, 10, 8259.

Botanical extracts - Caronositol (fertility)

High dose of d-chiro-inositol improves oocyte quality in women with polycystic ovary syndrome undergoing ICSI: a randomized controlled trial.

Mendoza N, Galan MI, Molina C, Mendoza-Tesarik R, Conde C, Mazheika M, Diaz-Ropero MP, Fonolla J, Tesarik J, Olivares M. Gynecol Endocrinol. 2020 May;36(5):398-401.

Prebiotic Fibre Papers

Evaluation of satiety enhancement, including compensation, by blends of gum arabic. A methodological approach

Calame W, Thomassen F, Hull S, Viebke C, Siemensma AD. Appetite. 2011 Oct;57(2):358-64. doi: 10.1016/j.appet.2011.06.005. Epub 2011 Jun 12

Gum arabic establishes prebiotic functionality in healthy human volunteers in a dose-dependent manner

Calame W, Weseler AR, Viebke C, Flynn C, Siemensma AD. Br J Nutr. 2008 Dec;100(6):1269-75. doi: 10.1017/S0007114508981447. Epub 2008 May 9. Erratum in: Br J Nutr.

Hypoglycemic effect of gum acacia in healthy human subjects

Sharma, R.D. Nutrition Research, 1985; 5:1437-1441


Wheat grainsThe effect of pre-treatment of protein ingredients for infant formula on their in vitro gastro-intestinal behaviour.

Bernard Corrigan, André Brodkorb. International Dairy Journal, Volume 110, 2020, 104810.

Ingestion of protein hydrolysate and amino acid-carbohydrate mixtures increases postexercise plasma insulin responses in men

van Loon LJ, Kruijshoop M, Verhagen H, Saris WH, Wagenmakers AJ. J Nutr. 2000 Oct;130(10):2508-13

The effect of different protein hydrolysate/carbohydrate mixtures on postprandial glucagon and insulin responses in healthy subjects

Claessens M, Calame W, Siemensma AD, van Baak MA, Saris WH. Eur J Clin Nutr. 2009 Jan;63(1):48-56. Epub 2007 Sep 12

The thermogenic and metabolic effects of protein hydrolysate with or without a carbohydrate load in healthy male subjects

Claessens M, Calame W, Siemensma AD, Saris WH, van Baak MA. Metabolism. 2007 Aug;56(8):1051-9

Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate

van Loon LJ, Saris WH, Verhagen H, Wagenmakers AJ. Am J Clin Nutr. 2000 Jul;72(1):96-105

Proteins Papers (Supporting)

Slow and fast dietary proteins differently modulate postprandial protein accretion

Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrère B. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14930-5

Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group

Deutz NE, Bauer JM, Barazzoni R, Biolo G, Boirie Y, Bosy-Westphal A, Cederholm T, Cruz-Jentoft A, Krznariç Z, Nair KS, Singer P, Teta D, Tipton K, Calder PC. Clin Nutr. 2014 Dec;33(6):929-36. doi: 10.1016/j.clnu.2014.04.007. Epub 2014 Apr 24

Fast-digestive protein supplement for ten days overcomes muscle anabolic resistance in healthy elderly men

Walrand S, Gryson C, Salles J, Giraudet C, Migné C, Bonhomme C, Le Ruyet P, Boirie Y. Clin Nutr. 2015 May 8. pii: S0261-5614(15)00130-2. doi: 10.1016/j.clnu.2015.04.020

Maximizing muscle protein anabolism: the role of protein quality

Tang JE, Phillips SM. Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):66-71. doi: 10.1097/MCO.0b013e32831cef75

The consumption of milk and dairy foods and the incidence of vascular disease and diabetes: an overview of the evidence

Elwood PC, Pickering JE, Givens DI, Gallacher JE. Lipids. 2010 Oct;45(10):925-39. doi: 10.1007/s11745-010-3412-5. Epub 2010 Apr 16

Influence of the protein digestion rate on protein turnover in young and elderly subjects

Dangin M, Boirie Y, Guillet C, Beaufrère B. J Nutr. 2002 Oct;132(10):3228S-33S

The rate of protein digestion affects protein gain differently during aging in humans

Dangin M, Guillet C, Garcia-Rodenas C, Gachon P, Bouteloup-Demange C, Reiffers-Magnani K, Fauquant J, Ballèvre O, Beaufrère B. J Physiol. 2003 Jun 1;549(Pt 2):635-44. Epub 2003 Mar 28

Hydrolyzed formulas for allergy prevention

Vandenplas Y, Bhatia J, Shamir R, Agostoni C, Turck D, Staiano A, Szajewska H. J Pediatr Gastroenterol Nutr. 2014 May;58(5):549-52. doi: 10.1097/MPG.0000000000000318

Meta-analysis of the evidence for a partially hydrolyzed 100% whey formula for the prevention of allergic diseases

Szajewska H, Horvath A. Curr Med Res Opin. 2010 Feb;26(2):423-37. doi: 10.1185/03007990903510317

Extensive and partial protein hydrolysate preterm formulas: the effect on growth rate, protein metabolism indices, and plasma amino acid concentrations

Szajewska H, Albrecht P, Stoitiska B, Prochowska A, Gawecka A, Laskowska-Klita T. J Pediatr Gastroenterol Nutr. 2001 Mar;32(3):303-9

Growth of healthy term infants fed partially hydrolyzed whey-based infant formula: a randomized, blinded, controlled trial

Borschel MW, Choe YS, Kajzer JA. Clin Pediatr (Phila). 2014 Dec;53(14):1375-82. doi: 10.1177/0009922814541804. Epub 2014 Jul 8

Short- and long-term effects of feeding hydrolyzed protein infant formulas on growth at < or = 6 y of age: results from the German Infant Nutritional Intervention Study

Rzehak P, Sausenthaler S, Koletzko S, Reinhardt D, von Berg A, Krämer U, Berdel D, Bollrath C, Grübl A, Bauer CP, Wichmann HE, Heinrich J; German Infant Nutritional Intervention Study Group. Am J Clin Nutr. 2009 Jun;89(6):1846-56. doi: 10.3945/ajcn.2008.27373. Epub 2009 Apr 15

Preventive effect of hydrolyzed infant formulas persists until age 6 years: long-term results from the German Infant Nutritional Intervention Study (GINI)

von Berg A, Filipiak-Pittroff B, Krämer U, Link E, Bollrath C, Brockow I, Koletzko S, Grübl A, Heinrich J, Wichmann HE, Bauer CP, Reinhardt D, Berdel D; GINIplus study group. J Allergy Clin Immunol. 2008 Jun;121(6):1442-7. doi: 10.1016/j.jaci.2008.04.021

A peptidomic analysis of human milk digestion in the infant stomach reveals protein-specific degradation patterns

Dallas DC, Guerrero A, Khaldi N, Borghese R, Bhandari A, Underwood MA, Lebrilla CB, German JB, Barile D. J Nutr. 2014 Jun;144(6):815-20. doi: 10.3945/jn.113.185793. Epub 2014 Apr 3

Cow’s milk allergens identification by two-dimensional immunoblotting and mass spectrometry

Natale M, Bisson C, Monti G, Peltran A, Garoffo LP, Valentini S, Fabris C, Bertino E, Coscia A, Conti A.
Mol Nutr Food Res. 2004 Oct;48(5):363-9

Z-score of weight for age of infants with atopic dermatitis and cow’s milk allergy fed with a rice-hydrolysate formula during the first two years of life

Savino F, Castagno E, Monti G, Serraino P, Peltran A, Oggero R, Fanaro S, Vigi V, Silvestro L. Acta Paediatr Suppl. 2005 Oct;94(449):115-9

Nutritional Lipids Papers (Supporting)

Oil and water mixingSummary of the scientific conference on dietary fatty acids and cardiovascular health: conference summary from the nutrition committee of the American Heart Association

Kris-Etherton P, Daniels SR, Eckel RH, Engler M, Howard BV, Krauss RM, Lichtenstein AH, Sacks F, St Jeor S, Stampfer M, Eckel RH, Grundy SM, Appel LJ, Byers T, Campos H, Cooney G, Denke MA, Howard BV, Kennedy E, Krauss RM, Kris-Etherton P, Lichtenstein AH, Marckmann P, Pearson TA, Riccardi G, Rudel LL, Rudrum M, Sacks F, Stein DT, Tracy RP, Ursin V, Vogel RA, Zock PL, Bazzarre TL, Clark J. Circulation. 2001 Feb 20;103(7):1034-9

Fatty acids in cardiovascular health and disease: a comprehensive update

Baum SJ, Kris-Etherton PM, Willett WC, Lichtenstein AH, Rudel LL, Maki KC, Whelan J, Ramsden CE, Block RC. J Clin Lipidol. 2012 May-Jun;6(3):216-34. doi: 10.1016/j.jacl.2012.04.077. Epub 2012 Apr 13

Plasma fatty acid changes following consumption of dietary oils containing n-3, n-6, and n-9 fatty acids at different proportions: preliminary findings of the Canola Oil Multicenter Intervention Trial (COMIT)

Senanayake VK, Pu S, Jenkins DA, Lamarche B, Kris-Etherton PM, West SG, Fleming JA, Liu X, McCrea CE, Jones PJ. Trials. 2014 Apr 23;15:136. doi: 10.1186/1745-6215-15-136

Docosahexaenoic acid and human brain development: Evidence that a dietary supply is needed for optimal development

Brenna JT, Carlson SE. J Hum Evol. 2014 Apr 26. pii: S0047-2484(14)00083-9. doi: 10.1016/j.jhevol.2014.02.017

n-3 LCPUFA improves cognition: the young, the old and the sick

Joffre C, Nadjar A, Lebbadi M, Calon F, Laye S. Prostaglandins Leukot Essent Fatty Acids. 2014 Jul-Aug;91(1-2):1-20. doi: 10.1016/j.plefa.2014.05.001. Epub 2014 May 14

Review of sn-2 palmitate oil implications for infant health

Bar-Yoseph F, Lifshitz Y, Cohen T. Prostaglandins Leukot Essent Fatty Acids. 2013 Sep;89(4):139-43. doi: 10.1016/j.plefa.2013.03.002. Epub 2013 Mar 27

Dietary medium-chain triacylglycerols versus long-chain triacylglycerols for body composition in adults: systematic review and meta-analysis of randomized controlled trials

Bueno NB, de Melo IV, Florêncio TT, Sawaya AL. J Am Coll Nutr. 2015;34(2):175-83. doi: 10.1080/07315724.2013.879844. Epub 2015 Feb 4

Health benefits, enzymatic production, and application of medium– and long-chain triacylglycerol (MLCT) in food industries: a review

Lee YY, Tang TK, Lai OM. J Food Sci. 2012 Aug;77(8):R137-44. doi: 10.1111/j.1750-3841.2012.02793.x. Epub 2012 Jul 2

Medium chain triglycerides. Monograph

Altern Med Rev. 2002 Oct;7(5):418-20

Galacto-oligosaccharides Papers (GOS) (Supporting)

Galacto-oligosaccharides are bifidogenic and safe at weaning: a double-blind randomized multicenter study

Fanaro S, Marten B, Bagna R, Vigi V, Fabris C, Peña-Quintana L, Argüelles F, Scholz-Ahrens KE, Sawatzki G, Zelenka R, Schrezenmeir J, de Vrese M, Bertino E. J Pediatr Gastroenterol Nutr. 2009 Jan;48(1):82-8. doi: 10.1097/MPG.0b013e31817b6dd2

Prebiotics in infant formulas

Boehm G, Jelinek J, Stahl B, van Laere K, Knol J, Fanaro S, Moro G, Vigi V. J Clin Gastroenterol. 2004 Jul;38(6 Suppl):S76-9. Review

Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants

Moro G, Minoli I, Mosca M, Fanaro S, Jelinek J, Stahl B, Boehm G. J Pediatr Gastroenterol Nutr. 2002 Mar;34(3):291-5

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